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IrisGo, a startup backed by Andrew Ng, looks to become the AI desktop buddy you never knew you needed

Industry insiders say the next big thing in AI is “proactive” systems: agents that can anticipate a user’s needs — and fulfill them — before the user even knows what those needs are.

One startup that’s looking to make headway in this area is IrisGo. The company, which closed a $2.8 million seed round led by Andrew Ng’s AI Fund earlier this year, is building a desktop companion for PCs that can learn about a user’s daily workflows and then automate them with limited to no human prompting.

IrisGo was co-founded by Jeffrey Lai, a former Apple engineer who helped to build the Chinese language version of Siri, the company’s automated assistant. (Somewhat slyly, Iris is Siri spelled backward.)

The core idea is simple: Show the program how to do something once, and it remembers that process for future automated use — no repeat instructions needed.

During a conversation with TechCrunch, Lai ran a demo, showing how his platform could learn to place a coffee order online. As I watched, IrisGo recorded the steps it took to select a latte from Philz Coffee (a popular Bay Area chain), fill out credit card information, and then hit purchase. Lai then asked IrisGo to repeat the order on its own; the agent dutifully complied.

Buying coffee, of course, is not really the point. Instead, the hope is that the system will automate a whole host of business-related tasks. Iris comes with a built-in “skills” library — things like email drafting, invoice processing, report building, document summarization, and many other ready-to-use automated workflows. At the same time, Iris learns from the user’s desktop behavior and automatically adds those tasks to its potential list of action items.

The application also includes a coding assistant — similar in concept to OpenAI’s Codex or Anthropic’s Claude Code — designed to assist developers as they go about their work.

“Our target audience is knowledge workers — white-collar companies. There’s a lot of repetitive tasks that those workers do every day,” Lai said, noting that, despite the high-octane power of today’s frontier models, AI-assisted office work can still feel incredibly manual and repetitive. The goal, he said, is to move away from that and toward a more fully autonomous workflow, where the human works on high-level conceptual work while agentic systems take care of all the clerical work in the background.

A particularly appealing feature of IrisGo is that it is designed to process a lot of data on-device, giving it stronger privacy protections than other applications that rely heavily on the cloud. Lai says that the system is still a hybrid architecture — meaning that larger, more complex tasks are ultimately processed through the cloud, although the company promises that cloud processing “only occurs when explicitly authorized by the user and uses end-to-end encryption.”

Part of the strategy for scaling Iris has been to garner credibility through association with prominent figures and organizations. Support from Ng — notably a co-founder of the formative deep learning research team Google Brain — has helped. Lai managed to set up a meeting with Ng through a shared connection: Both are alumni from Carnegie Mellon University. Lai and his co-founder demoed Iris during that meeting, and Ng’s AI Fund ultimately led the startup’s seed round. Nvidia and Google have also backed the company.

IrisGo recently launched the beta versions of its macOS and Windows apps, and the company is also currently pursuing deals with laptop companies to preinstall the app on new devices. It recently struck such a deal with Acer, and Lai said the hope is that the company can strike similar deals with other device makers soon.

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Imperagen raises £5 million to use quantum physics, AI on enzyme engineering

Biotech company Imperagen announced on Thursday a £5 million ($6.7 million) seed round led by PXN Ventures, with participation from IQ Capital and Northern Gritstone. The company was founded in 2021 by Manchester Institute of Biotechnology scientists Dr. Andrew Currin, Dr. Tim Eyes, and Dr. Andy Almond and spun out of the university.

The startup seeks to improve enzyme engineering by making it faster, more efficient, and less costly than the slower, more physical, trial-and-error-focused process used now.

Imperagen is using three core technologies as it seeks to redefine enzyme engineering. Specifically, it uses a quantum physics-based simulation instead of trial-and-error enzyme mutations in a lab. Imperagen predicts the behavior of enzyme variants on a computer using advanced quantum physics modeling that can explore millions of mutations, the company said. Then it translates this information into its custom AI models, trained on the enzyme problems Imperagen seeks to explore. Finally, to retain its AI models, Imperagen uses robots and automation to generate experimental data, which is fed back to the AI model, in a process called closed-loop simulation.

Enzymes are incredibly important across many industries, especially in pharmaceuticals, as they are essential to drug development. Startups like Imperagen are hoping to speed up enzyme engineering because it can have a domino effect, making, for example, drug discovery faster and more efficient. Enzymes are also used in sectors like food, biofuels, and agriculture. Experts in sustainability are also looking to enzymes — and the AI technologies surrounding them — to make industrial production and manufacturing more sustainable. 

Others in this space include Biomatter, Cradle Bio, and Absci.

On Thursday, Imperagen also announced that Guy Levy-Yurista will assume the role of CEO. Speaking to TechCrunch, he said that right now, the process of enzyme engineering is falling short, where even many new AI-powered technologies can pass trial and error but fail when put into practice on an industrial scale.

Imperagen hopes its tech will make enzyme development “faster, more reliable, and more commercially accessible, helping companies bring better bio-based products to market without the long timelines and uncertainty that have traditionally held the field back,” he told TechCrunch. 

Levy-Yurista has a background in AI, life sciences, and enterprise technology. Though the founders will remain at the company, Levy-Yurista was brought in to help build out its new technologies, including a vertical AI infrastructure for biocatalysis (a process that accelerates chemical reactions using natural catalysts like enzymes), while scaling the startup’s AI strategy, commercial models, and industrial partnerships. 

The company has raised £8.5 million ($11.42 million) in funding to date and the fresh capital will be used to hire more AI specialists, put toward research and development, expand its experimental lab capabilities, and build a go-to-market function within the next two years. 

“Ultimately, Imperagen hopes wider use of engineered enzymes will help industries reliably produce products that are cleaner, safer and better for people and the planet, while also making commercial sense for the companies that adopt them,” Levy-Yurista said. 

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General Catalyst just led a $63M bet on India’s travel payments market

Scapia, an Indian startup that combines travel booking with co-branded credit cards and mobile payments, has raised $63 million in a funding round led by General Catalyst, with existing investors Peak XV Partners and Z47 also participating. The deal comes despite a broader slowdown in fintech dealmaking.

The all-equity round assigns the startup a post-money valuation of more than $500 million, according to a source familiar with the matter, more than doubling its valuation from around $200 million in April 2025. The four-year-old outfit has raised $126 million to date from investors.

That General Catalyst, one of the most prominent U.S. venture firms, is leading the round suggests that India’s travel-focused fintech market is drawing serious attention well beyond its home region.

The funding also comes as investors globally grow more selective in fintech bets after years of aggressive funding. In India, fintech funding remained largely flat in Q1 2026, while the number of deals fell by more than half from a year earlier as investors concentrated capital into fewer, larger deals, per a recent report by Tracxn. By contrast, the U.S. saw fintech funding grow sharply, driven by large rounds for a handful of companies in areas including AI and crypto infrastructure.

Investors are betting Scapia can benefit from growing demand among younger Indians for apps that combine payments and travel bookings. Founded in 2022 by former Flipkart executive Anil Goteti, the startup’s app combines co-branded credit cards, UPI-based payments, travel bookings, and commerce in one place. UPI — India’s government-backed real-time payments network and one of the most widely used digital payment systems in the world — is central to how younger Indians move money today.

Over the past year, Scapia said flight bookings on its platform grew nearly six times, while hotel bookings increased about eightfold, with smaller Indian cities driving a growing share of demand. Customer growth also rose sevenfold during the same period, the startup said, without disclosing absolute figures.

Scapia has seen strong adoption among younger travelers who increasingly want flexible travel rewards and integrated payment options instead of traditional credit card perks, Goteti said in an interview. He added that one-third of users now prefer airport dining and shopping rewards over lounge access.

“Lounges are getting quite crowded,” Goteti told TechCrunch. “People actually are looking for an experience outside the lounge.”

Scapia also offers a dual-network co-branded credit card using both Visa and RuPay — a government-backed Indian payment network — allowing users to access card payments and UPI-linked credit through a single statement, credit line, and repayment flow. Moreover, the startup partners with Federal Bank and BOBCARD to offer co-branded cards and plans to add another banking partner in the coming months, Goteti said.

The Bengaluru-based startup operates in a growing market for travel-focused financial products in India, competing with companies like Niyo — another Indian startup that combines banking and travel features — and travel platform Ixigo, while global fintech firms including Revolut are also eyeing the country.

Scapia, which has about 250 employees, said the fresh funding will go toward expanding its product offerings and hiring more AI-focused engineering and product talent as competition intensifies in India’s consumer fintech market.

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Truecaller gets into the eSIM business to diversify its revenue streams

Caller ID company Truecaller launched eSIM services for travelers. The launch comes as the company aims to bolster its balance sheet and diversify business amid dipping ad revenues.

The company said its plans will range from 1 GB over 7 days to 20 GB over 30 days. Initially, the launch will make the eSIM product available in 29 countries.

The list includes Italy, Sweden, Spain, France, Germany, Poland, Portugal, Romania, the Netherlands, Belgium, Ireland, Austria, Finland, the Czech Republic, Denmark, Hungary, the United States, the United Kingdom, Australia, Canada, New Zealand, Switzerland, Norway, Chile, Indonesia, Malaysia, South Africa, Egypt, and Nigeria.

Notably, the company’s biggest market, India, is missing from the list. This is likely due to the country’s strict telecom regulations. Previously, the country blocked Airalo and Holafly over concerns around fraudulent use.

Truecaller said it is working with global cellular connectivity provider Telna and telecom software provider Telness Tech to operate the eSIM platform.

Where there are other eSIM providers like Airalo, Holafly, Roamless, and NordVPN’s Saily, Truecaller thinks that its existing user base of over 500 million will prove beneficial for acquiring new users.

“The starting point is different from other players in the category. They have had to build their audiences from zero. We are offering travel eSIM inside our app that over 500 million people already use and trust every month,” Truecaller chief operating officer Fredrik Kjell told TechCrunch over email.

“These are established relationships, with a large number of people having used Truecaller for many years. That changes distribution and pricing,” said Kjell.

Kjell also said that this is a strategic move for Truecaller that makes the app more usable for users. This comes at a critical time for the company. Last week, the company slashed 70 jobs across many teams. Plus, it posted disappointing Q1 2026 numbers. Truecaller’s net sales dropped 27% to 362 million SEK ($39.34 million), and ad revenues declined by 44%.

The company is leaning into increasing subscription revenues with features like AI Assistant and Family Protection. During times when ad revenue is shaky, additional services like eSIM could provide newer money-making avenues.

As TechCrunch reported last year, eSIM adoption is on the rise thanks to travel and device compatibility. Investors are also interested in putting money into eSIM startups. Within the last 12 months, startups like Airalo, Roamless, Kolet, eSIMo, and Truley raised millions of dollars.

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