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Breakout Ventures raises $114M fund to back AI science startups

Breakout Ventures has closed a $114 million Fund III to back AI-focused early-stage startups working in scientific fields such as biology and chemistry. 

The firm has already written checks to three companies and plans to invest in at least 20 companies through this fund, with average check sizes ranging from $500,000 to $5 million. Lindy Fishburne, managing director of Breakout Ventures, told TechCrunch the firm was looking for companies focused on “unlocking the complexity of science with AI.”

Breakout spun out of a grant program from the Thiel Foundation and officially launched in 2016. It has previously raised two funds: a $60 million Fund 1 in 2017 and a $112.5 million Fund II in 2021, also focused on science startups. 

“We’ve always been focused on the opportunity for technology to unlock the power of biology and chemistry to solve massive unmet needs and create new markets,” she told TechCrunch. 

It took around a year and a half to raise Fund III, she said, from limited partners, including The Kraft Group, Pinegrove Venture Partners, and S-Cubed Capital.

“Breakout founders may be PhDs who developed the science they are commercializing, or they may be emerging from industry where they deeply understand the need and opportunity,” she said. “Either way, we look for fit — the obvious reason why this is the best person to build a specific company.” 

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Hacker broke into FBI and compromised Epstein files, report says

An unidentified foreign hacker broke into the FBI’s field office in New York in 2023 and compromised files related to the bureau’s investigation into the sex offender Jeffrey Epstein, according to Reuters.

The newswire cited a source familiar with the breach, as well as court documents, and reported that the hack took advantage of a server at the Child Exploitation Forensic Lab in the FBI’s New York field office that was inadvertently left vulnerable by an FBI special agent working on the case. The breach “included combing through certain files pertaining to the Epstein investigation,” according to a court document. 

An FBI spokesperson said that the investigation is ongoing. “Following the 2023 cyber incident, the FBI contained the affected network and determined the incident to be an isolated one. The FBI restricted access to the malicious actor and rectified the network,” the spokesperson said in a statement sent by email to TechCrunch.

A source told Reuters that the hacker did not realize they had broken into the FBI until the agents asked them to join a video call where they showed their credentials to the hacker.

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Poppi founder on TikTok, Super Bowl ads, and her return to Shark Tank

For years, venture capitalists have been skeptical of beverage startups, citing thin margins and brutal distribution as reasons most brands never break out. But a new wave of “functional soda” companies has been challenging that assumption, including Poppi, the prebiotic soda brand that grew from a kitchen experiment into a $1.95 billion acquisition by PepsiCo

On this episode of TechCrunch’s Equity podcast, is joined by Poppi co-founder Allison Ellsworth to talk about building a beverage startup in a venture world dominated by SaaS and AI. From pitching on Shark Tank while nine months pregnant to going viral on TikTok and buying a last-minute Super Bowl ad, Ellsworth breaks down what it really takes to build a category-defining consumer brand — and what she looks for now that she’s back on Shark Tank as an investor herself.

Subscribe to Equity on YouTube, Apple Podcasts, Overcast, Spotify and all the casts. You also can follow Equity on X and Threads, at @EquityPod. 


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VC mega-funds are back with General Catalyst, Spark rumored to be raising billions

Following news last month that New York’s hottest venture firm, Thrive, just raised $10 billion for a new fund — its largest ever, double the previous one — another big-name VC firm is attempting to equal that raise. General Catalyst is in talks to raise $10 billion, unnamed sources tell Bloomberg. This firm, which has recast itself as a broader financial services company, raised $8 billion just a couple of years ago in 2024.

Meanwhile, Spark Capital is trying to raise $3 billion, sources tell The Information, which would also be a big boost from its previous funds. And, as TechCrunch just exclusively reported, Founders Fund is about to close a new $6 billion fund, too.

All of this follows Andreessen Horowitz’s $15 billion in new funding announced in January.

Venture firms were already sitting on a record amount of dry powder, meaning money available but not yet invested, at the end of 2025, according to the year-end report by PitchBook and the National Venture Capital Association. But 2026 is already shaping up to be a year of bigger and more, at least for venture firms with name recognition and enviable portfolios.

The obvious prediction is that VCs have plenty of money to keep fueling seed-stage AI startups with huge initial rounds and valuations. Record-breaking funding rounds for startups (as long as they are AI) will likely continue to be the new normal for 2026.

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