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Best 12 vs 5 NCAA Tournament Upset Picks for 2026 March Madness

Jan 27, 2026; Nashville, Tennessee, USA; Vanderbilt Commodores guard Tyler Tanner (3) reacts after a made three point basket against the Kentucky Wildcats during the second half at Memorial Gymnasium. Mandatory Credit: Steve Roberts-Imagn ImagesJan 27, 2026; Nashville, Tennessee, USA; Vanderbilt Commodores guard Tyler Tanner (3) reacts after a made three point basket against the Kentucky Wildcats during the second half at Memorial Gymnasium. Mandatory Credit: Steve Roberts-Imagn Images

The 12 versus 5 matchup in the tournament is always the trendy upset pick, but that might not be the case this season. 

The five seeds look very strong, while the twelve seeds will be fighting a steeper up hill climbin than usual. With that being said, five seeds have only gone undefeated five times since 2000, so having one upset on your bracket is probably a smart call. 

Here are the twelve seeds that I think have the best chance to play Cinderella in the first round.

#12 UNI (+470) vs #5 St. John’s -10.5

St. John’s is a dark-horse final-four team on a lot of brackets at the moment. The Big East champions, led by Rick Pitino, play a completely different brand of basketball from UNI. St John’s is going to speed the game up by applying full-court pressure and creating turnovers and extra possessions on offensive rebounds. The Panthers, on the other hand, play at the third-slowest tempo in the nation and the slowest of any team in the tournament.

In March, if you can limit the total number of possessions in a game, while shooting efficiently, you’ve got a great chance of pulling off an upset. UNI shot 41% from three over their four-game run through the Missouri Valley Conference to steal the conference as the 6 seed. St John’s played some of their best basketball in the Big East tournament, but we saw that happen last season, and then the Johnnies faltered out early, when they weren’t able to speed up the game in the tournament. 

Too many people have St. John’s going on a deep run when they should be far more worried about this first-round matchup.

#12 Akron (+260) vs #5 Texas Tech -7.5

Mar 7, 2026; Provo, Utah, USA; Texas Tech Red Raiders guard Christian Anderson (4) reacts to a made three point shot during the second half against the BYU Cougars at Marriott Center. Mandatory Credit: Aaron Baker-Imagn ImagesMar 7, 2026; Provo, Utah, USA; Texas Tech Red Raiders guard Christian Anderson (4) reacts to a made three point shot during the second half against the BYU Cougars at Marriott Center. Mandatory Credit: Aaron Baker-Imagn Images

Akron is one of the trendy 12 seeds this season. They’re a veteran team, making their third straight appearance in the tournament, while Texas Tech can be a great team, but their ceiling feels very limited with the injury to their leader, JT Toppin.

The Zips have been a bit of a KenPom darling all season long. 

They had been the highest-ranked MAC team despite losing to undefeated Miami in the regular season. Akron and Texas Tech have the closest margin in KenPom ratings among the 12 vs 5 games because Akron has been such an efficient offense all season. They shoot threes at 38.5% and can keep pace with a Texas Tech team that scores 80 points per game. The only reason I don’t have this in my No. 1 slot is Texas Tech’s defense. 

Their entire game plan relies on them preventing threes, and if Tavari Johnson and Shammah Scott struggle to generate offense in the paint, the Red Raiders could beat up on an off-shooting Zips squad.

#12 High Point (+390) vs #5 Wisconsin -10.5

Mar 7, 2026; West Lafayette, Indiana, USA; Wisconsin Badgers guard Nick Boyd (2) drives to the basket during the first half against the Purdue Boilermakers at Mackey Arena. Mandatory Credit: Jacob Musselman-Imagn ImagesMar 7, 2026; West Lafayette, Indiana, USA; Wisconsin Badgers guard Nick Boyd (2) drives to the basket during the first half against the Purdue Boilermakers at Mackey Arena. Mandatory Credit: Jacob Musselman-Imagn Images

Unlike the first two games mentioned, I would be very shocked to see upsets in these next two games. Similar to Akron, High Point is a popular upset pick this season. Everyone is looking at their 30-4 record and 10th-ranked offense in the nation in points per game, and believes they can pull off the upset. I don’t think there’s much of a chance that happens.

High Point is going to shoot a ton of threes and try to turn you over, but I think that plays right into Wisconsin’s strengths. 

Nick Boyd is one of the best guards in the country, and the exact type of player you want leading your team in the tournament. He averaged 25 points a night in the Big 10 tournament, and 6 times. He’s the type of player Wisconsin can look to in big moments to control the game score at will against a bad Panthers defense. There’s a reason the largest discrepancy of KenPom ratings comes from these two in the twelve versus five round. The Badgers are a very solid team, and if they had Nolan Winter, they would have been a dark-horse Final Four team for me. Still, I definitely like them here in the round of 64.

McNeese St (+520) vs Vanderbilt -11.5

Maybe I’m still too caught up on the horrible performance McNeese St had in the tournament last season, but I don’t think they have any chance to pull this upset off. Vanderbilt is one of the most underseeded teams in March Madness, but they were paired with a Cowboys team that they match up exceedingly well with.

I don’t love it when underdogs need to rely on turnovers to win games in March. The Cowboys have a surprisingly efficient defense (41st in the country) but an offense that barely makes it into the top 100. I also don’t love an efficient small-conference defense that can’t translate that same level of success when they play against a team as strong as Vanderbilt. The Commodores have such great guard play with Duke Miles and Tyler Tanner, and I don’t see them turning the ball over enough to keep McNeese St in this. I love Vanderbilt in this game at -11.5, and I also don’t mind them as a Final Four team at +1100.

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March Madness Cinderella Picks: Three Teams Ready to Bust Brackets

College basketball programs are handing out more money than ever to stack their rosters. Kentucky reportedly spent $22 million to keep four players from last year’s Sweet 16 squad and lure eight new ones.

Admittedly, the Wildcats aren’t a great example of maximizing your dollars considering they settled for a No. 7 seed in this NCAA Tournament, but many schools have learned how to marshal their ample resources to build the most efficient machines in college hoops history.

As recently as 2022, Gonzaga (+32.97) was the only school who entered the NCAA Tournament with a KenPom efficiency margin above the exalted plus-30 threshold. Only 15 teams exceeded the plus-20 mark.

As this year’s Tournament begins, we have eight schools higher than plus-30 (Duke, Arizona, Michigan, Florida, Houston, Iowa State, Illinois and Purdue) and 32 schools better than plus-20.

The rich are going to keep getting richer, smarter and stronger. Their coaches are de facto CEOs. Their conferences are transforming into oligarchies.

But they’re never going to find a way to stamp out Cinderellas.

Last year, we had Drake (No. 11 seed), McNeese (No. 12) and Colorado State (No. 12) ousting the big dogs in the first round.

In 2024, we enjoyed Duquesne (11), Grand Canyon (12), James Madison (12) and Yale (13).

In 2023, 15th-seeded Princeton barged into the Sweet 16 while Furman (13) and Fairleigh Dickinson (16) fostered more than their share of March Madness.

In 2022, 15th-seeded Saint Peter’s came up one win shy of the Final Four.

So which schools are going to smash their glass slipper over the head of a power conference school that looks too big and blustery to fail?

We’ve got three for you. For starters, keep in mind that in three of the last four NCAA Tournaments, two 12 seeds have upended No. 5 seeds in the first round.

This year? Those schools will be High Point, which battles Wisconsin on Thursday afternoon, and Akron, which faces Texas Tech on Friday afternoon.

This is no shade on the Badgers (though they have lost their last three first-round games as the 5 seed) or the Red Raiders. It’s just that High Point and Akron have the profiles to pull the upsets.

High Point, which boasts all the confidence in the world thanks to the nation’s longest active winning streak at 14 games, ranks third nationally in scoring at 90 points per game. The Panthers are decent from 3-point range (35.6%) and feature three good scorers led by senior wing Terry Anderson (16.0 ppg, 6.0 rpg), but their superpower is their turnover margin. Only McNeese, another 12 seed with a legit chance to win Thursday, enjoys a better turnover margin than High Point’s plus-7.1 per game.

As for Akron, this marks the Zips’ third straight trip to the NCAAs. They’re old. They’re athletic. They push the pace. Oh, and they feature SIX legit 3-point shooters ranging from Shammah Scott (42.2%) to stretch five Amani Lyles (37.9%). They’re not particularly big, but neither is Texas Tech with All-American JT Toppin out for the year.

So who’s the third team destined to be Cinderella?

No. 13 seed Hofstra should give No. 4 Alabama a fright, but the Crimson Tide will be on extra high-alert (no pun intended) after losing No. 2 scorer Aden Holloway (16.2 ppg) on Monday when arrested for possession of marijuana not for personal use — a felony.

It says here Furman, the 15 seed, will strike just like in 2023 even though the Paladins’ resume isn’t anything special. They finished fifth in the Southern Conference. They didn’t face any power conference teams, but they lost to NCAA Tournament entrants High Point, Troy and Northern Iowa by a combined 45 points. They only shoot 32.7% from 3-point range.

It’s all the perfect guise to lull UConn into complacency.

The Paladins have a star freshman point guard in Alex Wilkins (17.7 ppg, 4.7 apg), they have size and experience everywhere else and they get to face a UConn squad with two inexplicable losses in the last month (Creighton and Marquette) and two shellackings at St. John’s hands.

Don’t like this idea? Then how about No. 14 Wright State taking out Virginia? No. 13 Cal Baptist stunning Kansas in its first NCAA Tournament game? No. 13 Troy preventing Nebraska from collecting its first NCAA triumph?

Give us one Cinderella. Give us six Cinderellas. In this case, there’s no such thing as too much of a good thing.

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Early NFL Free Agency Winners and Moves That Stand Out

Nov 7, 2024; Baltimore, Maryland, USA; Baltimore Ravens general manager Eric Decosta one the field before the game against the Cincinnati Bengals at M&T Bank Stadium. Mandatory Credit: Tommy Gilligan-Imagn ImagesNov 7, 2024; Baltimore, Maryland, USA; Baltimore Ravens general manager Eric Decosta one the field before the game against the Cincinnati Bengals at M&T Bank Stadium. Mandatory Credit: Tommy Gilligan-Imagn Images

Another day, another wide receiver for the San Francisco 49ers.

Signing Christian Kirk one week into free agency — one year, $6 million — wasn’t trumpeted as a huge win, but you better believe Brock Purdy did a dance move or two knowing what his new collection of receivers can do for a team challenged to keep multiple reliable sets of hands on the field last season.

Kirk joins Mike Evans as one-time No. 1 receivers outside of slot wideout Ricky Pearsall, a massive breakout candidate as the 49ers shuffle the decks and tight end George Kittle makes the slow recovery from Achilles surgery.

Is it enough to contend with Super Bowl champion Seattle? Or beat the well-armed Rams’ secondary?

Perhaps not, but the 49ers have also fueled their offense well historically via the draft.

Who else made a positive early offseason impression?

Las Vegas Raiders

Dec 14, 2025; Philadelphia, Pennsylvania, USA; Las Vegas Raiders defensive end Maxx Crosby (98) on the field after loss to the Philadelphia Eagles at Lincoln Financial Field. Mandatory Credit: Eric Hartline-Imagn ImagesDec 14, 2025; Philadelphia, Pennsylvania, USA; Las Vegas Raiders defensive end Maxx Crosby (98) on the field after loss to the Philadelphia Eagles at Lincoln Financial Field. Mandatory Credit: Eric Hartline-Imagn Images

The Raiders can’t receive a perfect grade for their offseason to date given the outcome of the Maxx Crosby trade … or can they?

Crosby still has value. A perennial Defensive Player of the Year candidate, he’ll wind up helping the Raiders by staying put or eventually moving on to bring back draft or player compensation for the early stage rebuild. But the scrapped trade on the Ravens’ end of the deal erased a clear plan to restock with draft picks.

Signing the top offensive lineman on the market was a power play for new coach Klint Kubiak’s zone scheme, where running back Ashton Jeanty should thrive.

It cost $13 million to move Geno Smith — the portion of his 2026 salary Las Vegas is picking up with the Jets kicking in less than half of that amount — and the Raiders still need more playmakers to make presumptive No. 1 overall pick Fernando Mendoza successful. But moving Smith is another deal that sets the course for a turnaround.

New England Patriots

Jan 10, 2026; Chicago, IL, USA; Green Bay Packers wide receiver Romeo Doubs (87) runs after the catch for a touchdown against the Chicago Bears during the first half of an NFC Wild Card Round game at Soldier Field. Mandatory Credit: David Banks-Imagn ImagesJan 10, 2026; Chicago, IL, USA; Green Bay Packers wide receiver Romeo Doubs (87) runs after the catch for a touchdown against the Chicago Bears during the first half of an NFC Wild Card Round game at Soldier Field. Mandatory Credit: David Banks-Imagn Images

Romeo Doubs was a fringe No. 1 receiver with the Packers but doesn’t have the sustained production to fetch top dollar. 

That’s where the Patriots are winners in the four-year deal with Doubs, who essentially replaces Stefon Diggs in the wide receiver room. Doubs has No. 1 traits and won’t need long to learn the trust of quarterback Drake Maye. Another score for New England was addressing the guard spot with Alijah Vera-Tucker. The 26-year-old is exactly the type of presence the Patriots lacked in the Super Bowl loss to the Seahawks.

Baltimore Ravens

Whether Crosby failed a physical or not, the Ravens lost reputation points across the league backing out of the deal with the Raiders. Maybe it was worth it. 

Baltimore reclaimed a pick in the top half of the first round, didn’t have to pay Linderbaum elite left tackle money ($81 million over three years) and signed 31-year-old edge rusher Trey Hendrickson after the deal turned into a debacle.

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No. 7 Saint Mary's strives for tournament breakthrough against No. 10 Texas A&M

NCAA Basketball: West Coast Conference Tournament Semifinal-Saint Marys vs Santa ClaraMarch 9, 2026; Las Vegas, NV, USA; Saint Mary’s Gaels forward Paulius Murauskas (23) shoots the basketball against Santa Clara Broncos guard Thierry Darlan (15) during the second half at Orleans Arena. Mandatory Credit: Kyle Terada-Imagn Images

Seventh-seeded Saint Mary’s is in the NCAA Tournament for the 12th time under coach Randy Bennett, but deep runs haven’t been part of the story.

The Gaels begin pursuit of a breakthrough experience when they face No. 10 seed Texas A&M on Thursday night in South Region first-round play at Oklahoma City.

Saint Mary’s (27-5) is making its fifth straight March Madness appearance but only once have the Gaels reached the Sweet 16 during Bennett’s 25 seasons. That was in 2010 when Saint Mary’s was a No. 10 seed and beat Richmond and Villanova before being routed 72-49 by Baylor.

Gaels guard Joshua Dent covets an extended run this time around.

“It’s cool being in this position now, but like we’ve been trying to say, we want to cement our legacy above some of these other (Saint Mary’s) teams,” Dent said. “No disrespect to them, but we want to get further and see what we can do.”

The Gaels lost to Alabama in the second round last year.

Saint Mary’s first reached the NCAA Tournament during Bennett’s reign back in 2005. That also was in Oklahoma City and the Gaels lost to Southern Illinois in the first round.

Saint Mary’s faced just three ranked teams this season – splitting with West Coast Conference power Gonzaga and losing to Vanderbilt in nonconference play.

Texas A&M (21-11) also struggled (0-4) against ranked teams but made the NCAA field for the fourth straight season.

First-year coach Bucky McMillan finds that satisfying after only one player — reserve walk-on Chris McDermott — returned from last season’s team.

“It means a lot,” McMillan said. “When we didn’t have a roster, we were piecing (it) together, a lot of people didn’t know, ‘Hey, could we get in (the field)?’ And I thought this group could. I did from the start.”

A big piece for the Aggies is seventh-year forward Rashaun Agee, who previously had stops at New Mexico State, Bowling Green and Southern California.

Agee leads Texas A&M in scoring (14.7 points per game) and rebounding (8.9) and set a school record with 13 double-doubles.

Agee expects the Aggies to have a long stay.

“Everybody knows that in this time of basketball, each one of us, players and coaches, this can change our lives,” Agee said.

Texas A&M struggled down the stretch with seven losses in 11 games. The Aggies were one-and-done in the Southeastern Conference tournament, falling 83-63 to Oklahoma.

McMillan was hoping the late slumber wouldn’t cost his team a spot in the Big Dance.

“The SEC is the toughest league in the country, top to bottom,” McMillan said. “To finish tied for fourth in that league, it would have been a travesty if these guys didn’t get the opportunity.”

The Aggies rank 15th nationally with 10.8 3-point makes per game. Ruben Dominguez (10.3 ppg) has a team-best 82, Rylan Griffen (11.6) has 63 and Pop Isaacs (10.1) has 59.

For Saint Mary’s, Paulius Murauskas leads in scoring (18.8), while Mikey Lewis ranks second at 14.2 and Dent third at 13.0. Lewis leads the Gaels with 67 treys.

Saint Mary’s won eight straight games before losing to Santa Clara in the WCC tourney semifinals. Still, Dent is confident the team can make a run.

“Obviously, we’re not going there to win one or two games,” Dent said. “We’re going there to win as much as we can. Like we say, it’s do or die at this point.”

This is the third meeting between the Gaels and Aggies. They split two matchups in the mid-1990s.

The winner draws a second-round matchup Saturday against No. 2 Houston or No. 15 Idaho.

–Field Level Media

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