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How to get into a16z’s super-competitive Speedrun startup accelerator program

Without a doubt, one of the hottest new startup accelerators in tech right now is Andreessen Horowitz’s Speedrun program. Launched in 2023, the accelerator has an acceptance rate of less than 1%. In a January blog post, the program said that over 19,000 startups pitched and fewer than 0.4% were accepted into the latest cohort. 

The program used to focus on gaming startups, then expanded into entertainment and media, and is now a “horizontal program,” Joshua Lu, the program’s general manager and a partner at a16z, told TechCrunch. Today, founders of any type of startup can apply, and the program runs for about 12 weeks in San Francisco. It once had a program in Los Angeles, but Lu said the focus will be on SF from now on. 

There are two cohorts a year, and around 50 to 70 startups are accepted into each. The program invests up to $1 million into each company, though the downside is that it’s a bit pricey. It typically invests $500,000 up front in exchange for 10% of the startup’s company via a SAFE note, and another $500,000 if the next round is raised within 18 months, at whatever terms agreed to by the other investors.

In comparison, Y Combinator typically takes a fixed 7% of the company for $125,000, with another $375,000 “invested on an uncapped MFN safe.”

Speedrun said its program is more “equity expensive” because of what it offers founders. It provides them with access to a16z’s advisory and business networks that assist with tasks like go-to-market, brand development, media strategy, and talent sourcing. Plus it offers the startups perks like $5 million in credits to vendors such as AWS, OpenAI, Nvidia, and Deel.

Given the high interest, and low acceptance rate, TechCrunch spoke to Lu for some tips on how startups can best stand out. The latest cohort began in January and will end in April with a Demo Day. Applications for the next cohort open in April, though it looks at off-season applications year-round, Lu said. 

Focus on the founding team  

Speedrun focuses on early-stage startups. Because of this, they really examine who is on the founding team and whether their skills complement each other, Lu said.

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“That doesn’t mean one has to be technical and one has to be commercial and one has to be marketing,” Lu said. It means that “we prefer not to see any glaring holes in capabilities or interests. We want the founding team to be self-aware and for that to be part of the hiring plan.”  

They also like to see teams that have worked together before or have a shared history. 

“There are lots of things that a founding team has to navigate in their startup journey and having a bit of pattern recognition, being able to work with each other, knowing how to disagree and how to come out the other side of a disagreement, those are all things people on founding teams with shared histories have an easier time with, on average,” he continued. 

Even though AI has lowered the barriers to building software, it’s still incredibly helpful for a founding team to be technical, Lu said. At the same time, because AI has made it much faster to build and validate hypotheses and get a product out there, Lu said the Speedrun team likes to see when a startup already has a little bit of market validation or traction for their product.

“Speedrun as a program is really great at helping teams pour gasoline on a very small spark or fire,” he said. “We look for teams that have endeavored to build and try to show us that there’s a little spark we can fan the flames on.” 

Limit the market “theory”

Lu said one common mistake founders often make in the application process is spending too much energy talking about the market theory or why there is a defined problem and why their solution is the right one. “All of that may be true,” he said.

At the same time, he added, even the biggest, most successful tech companies faced unexpected blockades when they were young, sometimes even pivoting completely. What a company thinks it’s going to build at the beginning isn’t necessarily what will make it successful at the end.

“What we really want to hear about is why this founding team is really good together,” he continued, “why they’re a great founding team, the best possible founding team to solve this particular problem.” And then on top of that, any validation on the idea itself. 

It’s okay to use AI for the application, but…

Lu said the program encourages every founder to use AI to “clean up” their application. He said there is now no excuse for grammar errors or misspellings given the rising sophistication of AI tools. He also said AI can help founders sort out their thoughts, making them clearer, more concise, and more coherent. 

But if AI did all the work in explaining the startup, that may backfire. If a founder makes it to the next round, it will be a live video-call interview. “At that point, their live narration explanation skills are going to be put to the test,” he said. So founders should be prepared to talk cogently about their startup without the help of AI.

Only about 10% of founders make it to the video-call stage. There are typically two to three investors on the judging panel at a time.

After the live interview, the team typically conducts a few more screening calls with the founders, and then a final decision on the cohort is made.

Be greedy to network

There are, of course, other accelerator programs for startups to choose from. Lu said Speedrun itself was inspired by some of these other programs. 

Still, he said, this accelerator prides itself on giving founders access to a large, specialized operating team. In fact, he said the best teams that get the most out of the program are the ones most “greedy about getting exposure to the amazing people and programs” Speedrun has to offer. 

Lu listed off just a few points: a16z has around 600 people, and 10% of that staff is on the investment team, he said; everyone else is an operator who supports the companies the firm works with. As a result, founders in Speedrun will have access to experts who can help with marketing, banking, finance, management, and many other functions. So it helps to know who the startup wants to connect with and why. 

“We tell founders that come through the program, what you get out of Speedrun is what you put into it,” he said. “We think founders who want to take advantage of world experts in many different domains early in their startup journey would be really smart to choose us.”

Advice from a founder in the program

Founder Mohamed Mohamed, who is in the recent cohort, just announced a $5 million raise for his proptech startup Smart Bricks led by a16z’s Speedrun. He was attracted to the program because he said it stood out as one of the few “explicitly designed for co-founders working on frontier AI applications,” and he picked it because he wanted a program that would allow him to “stress-test an ambitious technical vision.”

Mohamed said he treated the application like an internal strategy memo rather than a pitch. “Instead of polishing buzzwords, we focused on clarity — the real problem, why it’s structurally hard, and why our team is unusually well-positioned to solve it,” he said. “We were explicit about what was working, what wasn’t, and where we needed help. I think that honesty and clear articulation of why this problem matters” is what helped the company in the application process.

He called the whole process “rigorous but refreshingly thoughtful,” and said it was designed to understand how founders think, not just what they have built so far. “The conversations went deep into product architecture, data strategy, and long-term ambition. It felt closer to a partner-level discussion than a typical accelerator interview, which was a strong signal for us,” he said.

His overall advice is to be “intellectually honest and precise.” For example, he said in his application he avoided “over-optimizing” for the sake of hyping up his company. “If you’re vague, derivative, or overly defensive about your idea, it shows quickly. Don’t try to sound bigger than you are; clarity about where you actually are is far more compelling than inflated narratives,” he said.

In the end, “Speedrun isn’t looking for perfect companies; they’re looking for founders who can reason clearly about complex problems and build with conviction,” he said. “Articulate the hard parts of what you’re doing and why they’re worth tackling. Depth beats polish every time.”

Correction, story originally misstated YC’s investment for its 7%. It has been corrected.

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Twilio co-founder’s fusion power startup raises $450M from Bessemer and Alphabet’s GV

Inertia Enterprises has raised $450 million to build one of the world’s most powerful lasers, which it hopes will serve as the foundation of a grid-scale power plant the fusion startup intends to start construction on in 2030. Inertia Enterprises is building on technology developed at the Lawrence Livermore National Laboratory’s National Ignition Facility (NIF). The NIF is the site of the world’s only controlled fusion reactions that have reached scientific breakeven, in which the reaction releases more energy than it took to start. 

The Series A was led by Bessemer Venture Partners with participation from GV, Modern Capital, Threshold Ventures, and others. Inertia’s co-founders include Jeff Lawson, who co-founded Twilio and serves as its CEO; Annie Kritcher, who led the successful experiments at NIF; and Mike Dunne, a Stanford professor who helped Lawrence Livermore develop a power plant design based on NIF. Kritcher has remained in her position at Lawrence Livermore.

NIF’s breakeven experiments have been a key milestone on the road to widespread fusion power. However, considerable progress needs to be made before a fusion power plant can deliver electricity to the grid. For Inertia, that means building a laser capable of delivering 10 kilojoules 10 times per second.

The startup’s reactor relies on a form of fusion known as inertial confinement. In Inertia’s flavor of inertial confinement, lasers bombard a fuel target, compressing the fuel until atoms inside fuse and release energy. The technique is based on NIF’s designs, in which laser light is converted into X-rays inside the target. The X-rays are what ultimately heat and compress the fuel pellet.

Each of Inertia’s power plants will require 1,000 of its lasers bombarding 4.5 mm targets that cost less than $1 each to mass produce. By contrast, the NIF’s system uses 192 lasers to fire on painstakingly crafted targets that take dozens of hours to make. Inertia is betting that by using the same basic principles as NIF and applying a more commercial mindset, it can bring the costs down dramatically.

Inertia’s new round is the latest in a string of funding announcements from fusion startups in recent months. With this round and others, fusion startups have attracted more than $10 billion in investments. And at least a dozen companies have raised more than $100 million.

Last week, Avalanche said it had raised $29 million to advance its desktop-sized fusion reactor. Earlier this year, Type One Energy told TechCrunch it had attracted $87 million in investment in advance of a $250 million Series B that it’s currently raising. Last summer, Commonwealth Fusion Systems raised $863 million from dozens of investors, including Google, Nvidia, and Breakthrough Energy Ventures.

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Two fusion companies recently announced they were going public via reverse mergers. General Fusion said in January it would merge with acquisition company Spring Valley III in a deal that values the combined company at $1 billion. General Fusion had previously struggled to raise money from private investors. Earlier last month, TAE Technologies announced it would merge with Donald Trump’s social media company, Trump Media & Technology Group; the combined company would be worth $6 billion, according to the all-stock transaction.

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UpScrolled’s social network is struggling to moderate hate speech after fast growth

UpScrolled, a social network that caught fire after TikTok’s ownership change in the U.S., is facing a serious moderation problem. After growing to more than 2.5 million users in January, users have reported the app is not taking action on the creation of usernames and hashtags that contain racial slurs, and hasn’t been able to properly moderate harmful content.

After receiving tips from UpScrolled users, TechCrunch confirmed the existence of a wide range of racial slurs and hate speech being used in people’s usernames on the app. For instance, some usernames would feature the name of the slur itself, the slur combined with other words, or multiple slurs in a single username; other usernames contain hate speech, like “Glory to Hitler.”

After reporting these slurs to UpScrolled’s public email address, we received a response from that email that the company is “actively reviewing and removing inappropriate content,” and is working to expand its moderation capacity. The email advised us not to engage with bad-faith actors while the situation is resolved.

Days after reporting this activity on the app, the accounts with slurs in the usernames that were provided to UpScrolled via screenshots remained online.

In addition, slurs and hate speech can be found elsewhere in the app, including hashtags and text used alongside its photo or video content, TechCrunch found. Other harmful content was available, including text posts with racial slurs and hate speech, and photo and video content glorifying Hitler, based on TechCrunch’s review of the app.

TechCrunch wasn’t alone in identifying this problem; the ADL also published a blog post this month, noting that UpScrolled was becoming home to antisemitic and extremist content and designated foreign terrorist organizations, like Hamas and others.

UpScrolled, which was founded in 2025, claims on its website claims that the platform offers every voice “equal power.” The app has seen more than 4 million downloads on iOS and Android since June 2025, according to market intelligence provider Appfigures — a figure even higher than the startup’s self-reported number last month.

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But while UpScrolled’s FAQ explains the app doesn’t “censor opinions,” it does indicate that its policy is to restrict content that involves “illegal activity, hate speech, bullying, harassment, explicit nudity, unlicensed copyrighted material, or anything intended to cause harm.”

That guidance is similar to most modern-day social media platforms. It’s clear, however, that the company is struggling to enforce its rules.

It’s battle that social networks are often faced with — especially those that receive a large influx of new users in a short time period. Bluesky, for instance, faced issues with slurs in account usernames in July 2023, which led to users threatening to leave the site.

After UpScrolled’s initial reply to our inquiry, TechCrunch also received a response from the press account on Tuesday, which directed us to UpScrolled founder Issam Hijazi’s new video, where he addressed the issues with content moderation.

In the video, he confirmed that users have been uploading “harmful content” that goes against UpScrolled’s terms of service and the company’s beliefs.

“We are offering everyone the freedom to express and share their opinions in a healthy and respectful digital environment,” Hijazi said. To create that environment, he said the company is “rapidly expanding our content moderation team, and we are upgrading our technology infrastructure so we can catch and remove harmful content more effectively.”

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How AI changes the math for startups, according to a Microsoft VP

For 24 years, Microsoft’s Amanda Silver has been working to help developers — and in the last few years, that’s meant building tools for AI. After a long stretch on GitHub Copilot, Silver is now a corporate vice president at Microsoft’s CoreAI division, where she works on tools for deploying apps and agentic systems within enterprises.

Her work is focused on the Foundry system inside Azure, which is designed as a unified AI portal for enterprises, giving her a close view of how companies are actually using these systems and where deployments end up falling short.

I spoke with Silver about the current capabilities of enterprise agents, and why she believes this is the biggest opportunity for startups since the public cloud.

This interview was edited for length and clarity.

So, your work focuses on Microsoft products for outside developers — often startups that aren’t otherwise focused on AI. How do you see AI impacting those companies?

I see this as being a watershed moment for startups as profound as the move to the public cloud. If you think about it, the cloud had a huge impact for startups because it meant that they no longer needed to have the real estate space to host their racks, and they didn’t need to spend as much money on the capital infusion of getting the hardware to be hosted in their labs and things like that. Everything became cheaper. Now agentic AI is going to kind of continue to reduce the overall cost of software operations again, because many of the jobs involved in standing up a new venture — whether it’s support people, legal investigations — a lot of it can be done faster and cheaper with AI agents. I think that’s going to lead to more ventures and more startups launching. And then we’re going to see higher-valuation startups with fewer people at the helm. And I think that that’s an exciting world. 

What does that look like in practice?

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We are certainly seeing multistep agents becoming very broadly used across all different kinds of coding tasks, right? Just as an example, one thing developers have to do to maintain a codebase is stay current with the latest versions of the libraries that it has a dependency on. You might have a dependency on an older version of the dot-net runtime or the Java SDK. And we can have these agentic systems reason over your entire codebase and bring it up to date much more easily, with maybe a 70% or 80% reduction of the time it takes. And it really has to be a deployed multistep agent to do that.

Live-site operations is another one — if you think of maintaining a website or a service and something goes wrong, there’s a thud in the night, and somebody has to be on call to get woken up to go respond to the incident. We still do have people on call 24/7, just in case the service goes down. But it used to be a really loathed job because you’d get woken up fairly often for these minor incidents. And we’ve now built a genetic system to successfully diagnose and in many cases fully mitigate issues that come up in these live site operations so that humans don’t have to be woken up in the middle of the night and groggily go to their terminals and try to diagnose what’s going on. And that also helps us dramatically reduce the average time it takes for an incident to be resolved.

One of the other puzzles of this present moment is that agentic deployments haven’t happened quite as fast as we expected even six months ago. I’m curious why you think that is.

If you think about the people who are building agents, what is preventing them from being successful, in many cases, it comes down to not really knowing what the purpose of the agent should be. There’s a culture change that has to happen in how people build these systems. What is the business use case that they are trying to solve for? What are they trying to achieve? You need to be very clear-eyed about what the definition of success is for this agent. And you need to think, what is the data that I’m giving to the agent so that it can reason over how to go accomplish this particular task?

We see those things as the bigger stumbling blocks, more than the general uncertainty of letting agents get deployed. Anybody who goes and looks at these systems sees the return on investment.

You mention the general uncertainty, which I think feels like a big blocker from the outside. Why do you see it as less of a problem in practice?

First of all, I think that it’s going to be very common that agentic systems have human-in-the-loop scenarios. Think about something like a package return. It used to be that you would have a workflow for the return processing that was 90% automated and 10% human intervention, where somebody would have to go look at the package and have to make a judgment call as to how damaged the package was before they would decide to accept the return. 

That’s a perfect example where actually now the computer vision models are getting so good that in many cases, we don’t need to have as much human oversight over inspecting the package and making that determination. There will still be some cases that are borderline, where maybe the computer vision is not yet good enough to make a call, and maybe there’s an escalation. It’s kind of like, how often do you need to call in the manager? 

There are some things that will always need some kind of human oversight, because they’re such critical operations. Think about incurring a contractual legal obligation, or deploying code into a production codebase that could potentially affect the reliability of your systems. But even then, there’s the question of how far we could get in automating the rest of the process.

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